Role of Lymphotoxin-α in Cigarette Smoke-Induced Inflammation and Lymphoid Neogenesis
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چکیده
Role of Lymphotoxin-α in Cigarette Smoke-Induced Inflammation and Lymphoid Neogenesis Tine Demoor, Ken R. Bracke, Tania Maes, Bernard Vandooren, Dirk Elewaut, Charles Pilette, Guy F. Joos and Guy G. Brusselle Department of Respiratory Medicine, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent University Hospital, Ghent, Belgium. Department of Rheumatology, Laboratory of Molecular Immunology and Inflammation, Ghent University Hospital, Ghent, Belgium. Unit of Pneumology and Microbiology, Department of Pneumology, Cliniques Universitaires St-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
منابع مشابه
Role of lymphotoxin-alpha in cigarette smoke-induced inflammation and lymphoid neogenesis.
In chronic obstructive pulmonary disease (COPD), chronic inflammation is accompanied by peribronchial lymphoid aggregates. Lymphotoxin (LT)-alpha, crucial in secondary lymphoid organogenesis, may be involved in lymphoid neogenesis. We examined cigarette smoke (CS)-induced pulmonary lymphoid neogenesis and inflammation in vivo in LTalpha knockout (LTalpha(-/-)) and wild-type (WT) mice and studie...
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تاریخ انتشار 2009